姓名: | 潘建平 |
职务: | PI |
职称: | 教授 |
学历: | 博士研究生 |
专业: | 免疫学/病原生物学 |
所属院系: | 基础医学系 |
研究方向: | 感染免疫学 |
电话: | 0571-88206896 |
信箱: | jppan@zju.edu.cn |
个人简介
浙江大学医学部病原生物学系副主任、免疫学教授、博士研究生导师,中国免疫学会理事,浙江省免疫学会感染免疫专业委员会主任委员www.med126.com,浙江省抗癌协会肿瘤生物治疗委员会委员兼秘书,“International Journal of Cancer”、“Vaccine”等期刊审稿人。
主要研究方向:肿瘤免疫学,黏膜抗感染免疫的细胞和分子机制
在研科主要研项目:不同亚群PP-DC在B细胞向肠黏膜归巢和IgA产生中的作用及其机制(国家自然科学基金,30872325)
发表的主要论文:
1.Lu J, Zheng MH, Yan J, Chen YP, Pan J. Effects of vasoactive intestinal peptide on phenotypic and functional maturation of dendritic cells. Inter Immunopharmacol 2008; 8:1449-1454.
2.Pan J, Jin P, Yan J, Kabelitz D. Anti-angiogenic active immunotherapy: a new approach to cancer treatment. Cancer Immunol Immunother 2008; 57:1105-1114.
3.Weng Y, Sun J, Wu Q, Pan J. Regulatory effects of vasoactive intestinal peptide on the migration of mature dendritic cells. J Neuroimmunol 2007; 182: 48-54.
4.Shao P, Zhao LH, Chen Z, Pan J. Regulation on maturation and function of dendritic cells by Astragalus mongholicus polysaccharides. Inter Immunopharmacol 2006; 6: 1161-1166.www.med126.com
5.Pan J, Heiser A, Maret M, Steinmann J, Kabelitz D. Enhanced anti-metastatic effect of fetal liver kinase 1 and interferon-gamma fusion gene-modified dendritic cell vaccination. Gene Ther 2005; 12:742-750.
6.Pan J, Zhang M, Wang J, Wang Q, Xia D, Sun W, Zhang L, Yu H, Cao X. Intratumoral injection of interferon-gamma gene-modified dendritic cells elicits potent antitumor effects: effective induction of tumor-specific CD8+ CTL response. J Cancer Res Clin Oncol 2005; 131:468-478.
7.Pan J, Zhang M, Wang J, Wang Q, Xia D, Sun W, Zhang L, Yu H, Liu Y, Cao X. Interferon-gamma is an autocrine mediator for dendritic cell maturation. Immunol Lett. 2004; 94 : 141-151.
8.Pan J, Ju DW, Wang Q, Zhang M, Xia D, Zhang L, Yu H, Cao X. Dexamethosone inhibits the antigen presentation of dendritic cells in MHC class II pathway. Immunol Lett 2001; 76 (3): 153-161.
9.Zhang LH,Pan JP,Yao HP, et al. Intrasplenic transplantation of IL-18 gene-modified hepatocytes: an effective approach to reverse hepatic fibrosis in schistosomiasis through induction of dominant Th1 response. Gene Ther 2001; 8: 1333-1342.